Sell^tm2Alb

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Species

Mus musculus

Symbol

Sell^tm2Alb

Category

allele

Allele of gene

Sell

Transgenic Constructs

None

Synonyms

• E/P/I

Description

The Sell gene was disrupted by insertion of a puromycin resistance cassette in opposite orientation into the coding sequence via homologous recombination. The construct was injected into ES cells already carrying mutations in Sele and Selp. Clones where the targeting vector inserted in cis to the Sele and Selp mutations were used to produce triple selectin-null mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations