Allele/Variant

Tg(Ascl1-EGFP,-cre)1Jejo

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Ascl1-GIC
M1-GIC

Description

The transgene is a bacterial artificial chromosome (BAC), RPCI-428P2, bearing a 305 kb mouse genomic segment that contains the Ascl1 locus(98 kb of 5' and 206 kb of 3' of the start codon), in which the coding sequence of the gene has been replaced with an EGFP-IRES-CRE cassette. The GFP reporter expression is low but reflects the Ascl1 pattern throughout multiple stages and in multiple regions, including the caudal neural tube, the telencephalon and diencephalon, and sympathetic and enteric nervous systems.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Ascl1 (Mmu)

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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