Allele/Variant

Tlr9M2Btlr

Species
Mus musculus
Symbol
Tlr9M2Btlr
Category
allele
Allele of gene
Tlr9
Transgenic Constructs
None
Synonyms
  • CpG2
  • Tlr9CpG2
Description
The Cpg2 phenotype was identified in an ENU mutagenesis screen for mutants with impaired response to Toll-like receptor (TLR) ligands. The mutation is an A-to-T transversion at nucleotide position 3060 of the gene (Genbank Accession NM_031178) that results replacement of glutamine by leucine at amino acid position 985 of the receptor protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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