Allele/Variant

Tlr4lps-Btlr

Species
Mus musculus
Symbol
Tlr4lps-Btlr
Category
allele
Allele of gene
Tlr4
Transgenic Constructs
None
Synonyms
  • lps3
  • Tlr4lps3, defective lipopolysaccharide response 3
Description
The lps3 phenotype was identified in an ENU mutagenesis screen for mutants with impaired response to Toll-like receptor (TLR) ligands. The mutation is an A-to-T transversion at nucleotide position 2147 of the gene (Genbank Accession NM_021297) that results in replacement of aspartic acid by valine at amino acid position 709 of the receptor protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

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