Allele/Variant

Mapttm1(MAPT)Vln

Species
Mus musculus
Symbol
Mapttm1(MAPT)Vln
Category
allele
Allele of gene
Mapt
Transgenic Constructs
None
Synonyms
  • tau-KOKI
Description
A human MAPT cDNA encoding the longest tau isoform of 441 amino acids containing four repeats, with 2 N-terminal inserts replaced the endogenous mouse gene. Endogenous mouse Mapt protein is not expressed, and the inserted human gene is expressed in brain driven by a murine Thy1 promoter beginning at P15.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations