Sirt3^tm1.1Fwa

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Species

Mus musculus

Symbol

Sirt3^tm1.1Fwa

Category

allele

Allele of gene

Sirt3

Transgenic Constructs

None

Synonyms

• Sirt3^-

Description

A floxed neo cassette was inserted into intron 3 and an additional loxP site was inserted upstream of exon 2. Cre-mediated recombination was used to remove the neo cassette, exon 2 and exon 3. The absence of protein product was confirmed by western blot analysis on liver and brain extracts.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations