Allele/Variant

Tg(Ins2-Chrm3*)1Jwe

Species
Mus musculus
Symbol
Tg(Ins2-Chrm3*)1Jwe
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • beta-M3-Tg1
Description
The rat insulin 2 promoter was used to drive expression of the gene in beta cells. Chrm3 contains two modifications (an N-terminal 9 amino acid hemagglutinin epitope tag was added and a central portion of the third intracellular loop, Ala274 to Lys469, was deleted) that do not change its functionality but allow the researchers to distinguish it from the endogenous gene product.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations