Allele/Variant

Tln1tm4.1Crit

Species
Mus musculus
Symbol
Tln1tm4.1Crit
Category
allele
Allele of gene
Tln1
Transgenic Constructs
None
Synonyms
  • Tln1fl
Description
Coding exons one through four (second through fifth exons) are flanked by loxP sites. This allele was generated by in vivo, Cre recombinase-mediated deletion of a loxP-flanked neomycin resistance cassette from the first intron of Tln1tm4Crit in cre transgenic embryos homozygous for the latter allele (personal communication). Talin expression can be ablated in specific cell/tissue types by crossing homozygous mice with appropriate cre transgenic mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations