Allele/Variant

Tg(Ins2-rtTA)2Efr

Species
Mus musculus
Symbol
Tg(Ins2-rtTA)2Efr
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • Ins-rtTA
  • RIP7-rtTA
Description
A transgenic construct containing 9.5kb 5' regulatory sequence and first intron of the rat insulin 2 gene (RIP7) controlling the reverse tetracycline transactivator (rtTA), as well as the polyadenylation site sequence of the RIP7 gene was injected into fertilized (C57BL/6 X CBA)F2 mouse eggs. Founder line 2 with 10 copies of the transgene was established. When mice are crossed to transgenic mice carrying reporter genes, transgene expression is detected only in pancreatic islet beta cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations