Allele/Variant

Tg(Prnp-TBP*)105Xjl

Species
Mus musculus
Symbol
Tg(Prnp-TBP*)105Xjl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • TBP-105Q
Description
A transgenic construct containing the human TATA box binding protein, TBP, containing a 105 polyQ repeat expansion, under the control of the mouse prion protein promoter was injected into fertilized FVB/N mouse eggs. Founder line TBP-105Q was established. The 105 polyQ-expansion was detected in the cerebral cortex and cerebellum by Western blot analysis.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations