Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Prnp-TBP*)71-27Xjl
MGI:3772868Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Prnp-TBP*)71-27Xjl

Species
Mus musculus
Symbol
Tg(Prnp-TBP*)71-27Xjl
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • TBP-71Q-27
Description
A transgenic construct containing the human TATA box binding protein, TBP, containing a 71 polyQ repeat expansion, under the control of the mouse prion protein promoter was injected into fertilized FVB/N mouse eggs. A second founder line TBP-71Q-27 was established, in addition to line 71Q-16. The 71 polyQ-expansion is detected in the cerebral cortex and cerebellum by Western blot analysis.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page