Allele/Variant

Robo1tm1Wian

Species
Mus musculus
Symbol
Robo1tm1Wian
Category
allele
Allele of gene
Robo1
Transgenic Constructs
None
Synonyms
  • Dulox Robo-
  • Robo1-
Description
In a two step integration process a hyg cassette with a 5' loxP site was inserted upstream of exon 1 and a puromycin resistance cassette with a 3' loxP site was inserted upstream of exon 22. Cre-mediated recombination was used to delete exons 1 through 21. The absence of protein expression was confirmed by immunohistochemistry.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Phenotype
Annotation details
Source
References
abnormal embryonic/fetal subventricular zone morphologyMGI
abnormal neurite morphologyMGI
perimembraneous ventricular septal defect
MGI
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Disease Associations

No data available