Allele/Variant

Tg(Tcrb)HRBAll

Species
Mus musculus
Symbol
Tg(Tcrb)HRBAll
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • HRB TCR
Description
Rearranged Vbeta8.3-SGTGGSAETL TCRbeta chain was cloned from a population of CD8+ T cells that recognizes a 17-mer peptide from the C-terminus of Histone 4 family members presented on H2-Kb. The recombined gene segments were placed in a TCR expression vector and injected into blastocytes. This founder line contains only the beta chain transgene, which is functionally expressed in about 25% of CD8+ T cells.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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