Version: 8.0.0
Date: Tue Jan 28 2025
Syt11tm1Sud
MGI:3774591
Allele of Syt11
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Syt11tm1Sud

Species
Mus musculus
Symbol
Syt11tm1Sud
Category
allele
Allele of gene
Syt11
Transgenic Constructs
None
Synonyms
None
Description
A targeting vector was designed to place a LoxP-Flp-neomycin-Flp cassette in intron 1, a FLAG-(C)4-FLAG cassette in exon 2, and LoxP site in intron 2. Mutant protein expression levels are similar to those of the wildtype protein. Expression is brain-specific and localized in the neuronal soma and dendrites (presumably on cargo vesicles). Protein can be recognized using FLAG antibody by Western blot analysis, but not in brain sections and labeled cultures. No significant N-ethyl-maleimide-sensitive factor attachment protein receptor (SNARE) binding is observed in immunoprecipitation (IP) assays.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page