Version: 8.0.0
Date: Tue Jan 28 2025
Ptprjtm1.2Weis
MGI:3774766
Allele of Ptprj
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ptprjtm1.2Weis

Species
Mus musculus
Symbol
Ptprjtm1.2Weis
Category
allele
Allele of gene
Ptprj
Transgenic Constructs
None
Synonyms
  • CD148-
  • PtprjTM-
Description
A targeting vector was designed to introduce a loxP-flanked neomycin-resistance cassette in reverse transcriptional orientation to intron 17 and an additional loxP site to intron 18. Exon 18 encodes the transmembrane domain of the gene (also called CD148). Targeted animals were bred with BALB/c-background CMV-Cre transgenic female mice to delete the neomycin cassette and exon 18. Transmembrane domain-deleted mice were obtained and characterized. CD148 protein is not detected on any cells of hematopoietic origin by immunoblotting or flow cytometry.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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