Wwox^Gt(XG218)Byg

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Species

Mus musculus

Symbol

Wwox^Gt(XG218)Byg

Category

allele

Allele of gene

Wwox

Transgenic Constructs

None

Synonyms

• Wwox^gt

Description

A gene trap vector containing a beta-geo cassette was inserted into intron 4 and resulted in a fusion protein at exon 4. Real-time PCR shows that mRNA levels are reduced by 95% in embryos and 85-95% in adults, depending on tissue examined. Protein is undetectable in most adult tissues, however, low levels are detected in testes. This is a hypomorph.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations