Allele/Variant

Cyp11a1tm2Bcc

Species
Mus musculus
Symbol
Cyp11a1tm2Bcc
Category
allele
Allele of gene
Cyp11a1
Transgenic Constructs
None
Synonyms
  • Cyp11a1L
Description
The proximal SF-1 binding site in intron 1 was replaced with one in which the genetic sequence was altered from TAGCCTTGA to TAGaaTTGA. A floxed neo cassette with a 3' lox P site was inserted in intron 1 but was removed by germ-line, cre-mediated recombination. Expression of the protein product was reduced 7-fold in the adrenal and testis but was unaffected in the placenta and ovary.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations