Allele/Variant

Erbb2tm8.1(Erbb2)Mul

Species
Mus musculus
Symbol
Erbb2tm8.1(Erbb2)Mul
Category
allele
Allele of gene
Erbb2
Transgenic Constructs
None
Synonyms
  • Erbb2NT
Description
Single-cell embryos with one copy of the Erbb2tm8(Erbb2)Mul recombinant allele were microinjected with a plasmid containing Cre recombinase under the control of the chicken actin promoter. The actin promoter is expressed at the two-cell phase in the mouse embryo and results in direct excision of the floxed neo in the germline and places the Erbb2 cDNA insert under the control of the endogenous promoter in all tissues in which it is normally expressed.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
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