Allele/Variant

Tg(CAG-EGFP/CETN2)3-4Jgg

Species
Mus musculus
Symbol
Tg(CAG-EGFP/CETN2)3-4Jgg
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • Centrin 2-GFP
  • GFP-CETN2
Description
The GFP-CETN2 transgene was designed with a chicken beta-actin promoter (with cytomegalovirus immediate early enhancer and beta-actin intron) upstream of an EGFP-centrin 2 fusion protein (containing the full length human centrin 2 cDNA cloned in-frame into the C-terminal of enhanced green fluorescent protein), and followed by a beta-globin polyA sequence. Two lines were maintained (18-1 and 3-4) and line 3-4 was donated to The Jackson Laboratory. These lines show consistent, robust expression of GFP in centrosomes (particularly in cerebellar granule cells).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations