Tg(CAG-EGFP/CETN2)3-4Jgg

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Species

Mus musculus

Symbol

Tg(CAG-EGFP/CETN2)3-4Jgg

Category

allele

Allele of gene

None

Transgenic Constructs

None

Synonyms

• Centrin 2-GFP
• GFP-CETN2

Description

The GFP-CETN2 transgene was designed with a chicken beta-actin promoter (with cytomegalovirus immediate early enhancer and beta-actin intron) upstream of an EGFP-centrin 2 fusion protein (containing the full length human centrin 2 cDNA cloned in-frame into the C-terminal of enhanced green fluorescent protein), and followed by a beta-globin polyA sequence. Two lines were maintained (18-1 and 3-4) and line 3-4 was donated to The Jackson Laboratory. These lines show consistent, robust expression of GFP in centrosomes (particularly in cerebellar granule cells).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations