Rock2^tm1.1Liao

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Species

Mus musculus

Symbol

Rock2^tm1.1Liao

Category

allele

Allele of gene

Rock2

Transgenic Constructs

None

Synonyms

None

Description

A neo cassette with a 3' loxP site was inserted downstream of exon 3 and an additional loxP site was inserted upstream of exon 3. Cre-mediated recombination in ES cells was used to remove the neo cassette and exon 3. The absence of protein product from the allele was confirmed by a 50% reduction in protein in heterozygotes as determined by western blot analysis on heart and kidney extracts.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations