Allele/Variant

Ppp4ctm1.2Htn

Species
Mus musculus
Symbol
Ppp4ctm1.2Htn
Category
allele
Allele of gene
Ppp4c
Transgenic Constructs
None
Synonyms
  • PP4c-
  • Tbx6/Ppp4ctm1.2Htn
Description
A loxP site was inserted in between exons 4 and 5. A floxed neomycin resistance cassette was inserted downstream of exon 8 and also replaced the codons of the last 4 amino acids of Tbx6. Cre-mediated recombination removed the selection cassette. Northern blot analysis confirmed normal Ppp4c transcript expression in embryo. RT-PCR confirmed normal Tbx6 transcript expression. Cre-mediated recombination removed the selection cassette and exons 5 through 8.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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