Allele/Variant

Tg(GPD1)A2Bir

Species
Mus musculus
Symbol
Tg(GPD1)A2Bir
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • GPDH-A2
Description
The transgene comprises 12.3 kb of human genomic DNA containing the GPD1 gene, consisting of 3.5 kb of 5' flanking sequence, the 7.6 kb protein-coding region and 1.2 kb of 3' flanking DNA. The 5' flanking sequence includes the proximal and distal promoter regions. Founder line A2 has approximately 14 copies of the transgene. Mice exhibit a much higher level of transgene expression in the cerebral cortex and kidney than is normal for the endogenous gene.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations