Allele/Variant

Tg(Myh6-Cryab*R120G)708Rbns

Species
Mus musculus
Symbol
Tg(Myh6-Cryab*R120G)708Rbns
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CryABR120G
  • R120G-CryAB
Description
This transgene expresses a mutant form of murine Cryab containing a missense mutation (R120G). This missense mutation acts in a dominant-negative fashion. In addition to transgenic line 708, lines 25 and 134 were also produced. The transgene copy number of this line is 1.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations