Wap^tm2(rtTA)Kuw

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Species

Mus musculus

Symbol

Wap^tm2(rtTA)Kuw

Category

allele

Allele of gene

Wap

Transgenic Constructs

None

Synonyms

None

Description

The coding sequence for rtTA was inserted into the 5'-UTR along with a floxed neomycin selection cassette. The neo selection cassette was eliminated in founder line 7A3 by crossing properly targeted mice to Tg(MMTV-cre)1Mam transgenic animals. When mice were given doxycycline, transgene expression was restricted to mammary epithelial cells as determined by crosses with two different rtTA reporter strains.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations