Fasl^del1Hong

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Species

Mus musculus

Symbol

Fasl^del1Hong

Category

allele

Allele of gene

Fasl

Transgenic Constructs

None

Synonyms

• FasL^del

Description

A spontaneous mutation results in the small deletion of 5 nucleotides at the 5' end of the first intron, removing the invariant GT dinucleotide in the 5' splice consensus sequence. Splicing between the first and second exons is aberrant, generating non-functional polypeptides and creating a loss-of-function allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations