Allele/Variant

Hand2tm1Majh

Species
Mus musculus
Symbol
Hand2tm1Majh
Category
allele
Allele of gene
Hand2
Transgenic Constructs
None
Synonyms
  • Hand2flneo
  • Hand2loxpneop
Description
A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1. Quanitative RT-PCR analysis of jaws from E11 embryos indicated that transcript expression in homozygous embryos was only about 14% that of wild-type littermates. Therefore, this allele is a hypomorph.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations