Version: 8.0.0
Date: Tue Jan 28 2025
Hand2tm1Majh
MGI:3804207
Allele of Hand2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Hand2tm1Majh

Species
Mus musculus
Symbol
Hand2tm1Majh
Category
allele
Allele of gene
Hand2
Transgenic Constructs
None
Synonyms
  • Hand2flneo
  • Hand2loxpneop
Description
A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1. Quanitative RT-PCR analysis of jaws from E11 embryos indicated that transcript expression in homozygous embryos was only about 14% that of wild-type littermates. Therefore, this allele is a hypomorph.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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