Allele/Variant

Fzr1Gt(RRJ067)Byg

Species
Mus musculus
Symbol
Fzr1Gt(RRJ067)Byg
Category
allele
Allele of gene
Fzr1
Transgenic Constructs
None
Synonyms
  • Cdh1gt
Description
The pGT0Lxf gene trap vector, containing a splice acceptor signal followed by betageo (lacZ-neor fusion) cDNA, has integrated into intron 5 of the gene. Immunoblot analysis of homozygous mutant E9.5 whole-embryo lysates detects no FZR1 (CDH1) protein; tissues of heterozygous mutant mice express ~50% of wild-type FZR1 levels. X-gal staining of fixed whole heterozygous E9.5 embryos reveals expression of beta-galactosidase from the gene trap insertion widely throughout the embryo and the placenta.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
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