Allele/Variant

E2f3tm4Gle

Species
Mus musculus
Symbol
E2f3tm4Gle
Category
allele
Allele of gene
E2f3
Transgenic Constructs
None
Synonyms
  • E2f3a3bKI
  • E2f3a3bki
Description
A floxed neo cassette was inserted 108 bp upstream of the E2f3 isoform "a" start codon, the exon 1b open reading frame replaced the exon 1a open reading frame, and a third loxP site was inserted approximately 300 bp downstream of exon 1a. Western blot analysis of MEFs confirmed the absence of expression of the "a" isoform with retention of expression of the "b" isoform.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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