Allele/Variant

Tg(Nr2e1-cre/ERT2)1Gsc

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Tlx-CreER^T2

Description

This transgene consists of modified BAC containing the entire coding region of the Nr2e1 gene including flanking regulatory sequences 104 kb upstream and 30 kb downstream, and drives expression of a tamoxifen-inducible form of cre recombinase fusion protein which replaces part of exon 1 of the Nr2e1 gene. 6 lines were generated of which 3 lines are further analyzed. All three lines showed tamoxifen-inducible Cre activity in the developing forebrain. This is a representative record for all 3 lines.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Nr2e1

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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