Allele/Variant

Apobec3Rfv3-r

Species
Mus musculus
Symbol
Apobec3Rfv3-r
Category
allele
Allele of gene
Apobec3
Transgenic Constructs
None
Synonyms
None
Description
This gene locus controls recovery from viremia and leukemia induced by Friend virus (FV). This dominant allele is found in C57BL/6J, C57BL/10, and 129P2/OlaHsd strains and allows for recovery from both viremia and leukemia in H2b mice. Recovery from viremia only is seen in H2a mice. This allele produces a full length mRNA transcript (including exon 2) that encodes for a protein with potent anti-viral activity.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations