Allele/Variant

Xiaptm1Hs

Species
Mus musculus
Symbol
Xiaptm1Hs
Category
allele
Allele of gene
Xiap
Transgenic Constructs
None
Synonyms
  • XIAPdeltaRING
Description
The first two codons of the RING doman (C449 and K450) were replaced with STOP codons by homologous recombination. This mutation truncates the RING domain and the 13 amino acid sequence between the RING and C terminus. The frt-flanked neo cassette inserted into intron 2 was removed by germ line, flp mediated recombination.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations