Gjb4^tm1Kwi

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Species

Mus musculus

Symbol

Gjb4^tm1Kwi

Category

allele

Allele of gene

Gjb4

Transgenic Constructs

None

Synonyms

• Cx30.3^-
• Cx30.3^LacZ

Description

A lacZ gene with a nuclear localization signal followed by a frt-flanked neomycin selection cassette in the reverse transcriptional orientation was inserted into the starting codon of the gene locus. Founder mice were crossed with a FLP-deleter strain to remove the neomycin selection cassette. Gene inactivation was confirmed by immunoblot analysis of skin lysates. LacZ expression was detected in the skin, kidney, and a subpopulation of cells in the apical layer of the vomeronasal organ.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations