Allele/Variant

InsrRgsc294

Species
Mus musculus
Symbol
InsrRgsc294
Category
allele
Allele of gene
Insr
Transgenic Constructs
None
Synonyms
  • InsrN1154S
  • M100294
Description
This mutatation, identified in an ENU mutagenesis screen, comprises an A to G transition in exon 18 that results in the substitution of serine for asparagine at amino acid position 1154 (N1154S), in the tyrosine kinase domain of the receptor.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Phenotype
Annotation details
Source
References
hyperglycemia
MGI
increased circulating insulin level
MGI
increased urine glucose level
MGI
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Disease Associations