Allele/Variant

Hsd11b1tm1.1Ggla

Species
Mus musculus
Symbol
Hsd11b1tm1.1Ggla
Category
allele
Allele of gene
Hsd11b1
Transgenic Constructs
None
Synonyms
None
Description
A floxed neo cassette was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Cre-mediated recombination removed the neo cassette and exon 5. RT-PCR confirmed the absence of transcript expression in the liver, tibialis anterior amd soleus. The absence of enzymatic activity was confirmed.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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