Version: 8.0.0
Date: Tue Jan 28 2025
Atg16l1tm1Aki
MGI:3818483
Allele of Atg16l1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Atg16l1tm1Aki

Species
Mus musculus
Symbol
Atg16l1tm1Aki
Category
allele
Allele of gene
Atg16l1
Transgenic Constructs
None
Synonyms
  • Atg16L1delta
Description
Exons 3, 4 and 5 that encode the coiled-coiled domain of the gene product were replaced with a neomycin resistance cassette. Immunoblotting of homozygote embryonic fibroblast lysate indicated two truncated proteins were produced. Ectopic expression of similar truncated proteins in wild-type embryonic fibroblasts indicated that the truncated proteins do not interfere in a dominant negative manner with autophagy processes.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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