Allele/Variant

Atg16l1Gt(XR0164)Wtsi

Species
Mus musculus
Symbol
Atg16l1Gt(XR0164)Wtsi
Category
allele
Allele of gene
Atg16l1
Transgenic Constructs
None
Synonyms
  • ATG16L1Hm2
Description
A gene-trap vector containing a splice acceptor followed by a beta-geo cassette disrupted the gene locus by inserting within the intronic region after exon 10. Protein expression of both the alpha and beta isoforms of the gene product were 23-37% of wild-type as determined by immunoblots of ileal lystates from homozygotes. This is a hypomorphic allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations