Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Tg(CAG-LacZ,-ACVR1*,-EGFP)35-1Mis
- Species
- Mus musculus
- Symbol
- Tg(CAG-LacZ,-ACVR1*,-EGFP)35-1Mis
- Category
- allele
- Allele of gene
- None
- Transgenic Constructs
- Synonyms
- CAG-Z-EGFP-caAlk2
- Description
- The modified chicken beta-actin promoter (CAG) was used to drive ubiquitous expression of a floxed LacZ gene with a triple polyadenylation signal sequence followed by a constitutively active human ACVR1 sequence with the amino acid substitution of glutamine with aspartic acid at position 207 (Q207D), an IRES sequence, and the EGFP coding sequence and a poly(A) signal. Five lines were established and expression analysis for one line (line 35-1) confirmed general, but not ubiquitous, expression of LacZ and cre-dependent general expression of the modified ACVR1 and EGFP.
- Additional Information
- Literature
Transgenic Constructs
This allele contains 1 transgenic construct- Symbol
- Expressed Components
- Knock-down Targets
- None
- Regulatory Regions
- None