Allele/Variant

Tg(Myh7-Ptpn11*Q79R)11Rbns

Species
Mus musculus
Symbol
Tg(Myh7-Ptpn11*Q79R)11Rbns
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • beta-MHC-Q97R11
Description
The promoter was used to drive expression of Ptpn11 containing the amino acid substitution of arginine for glutamine at position 79 in the fetal heart. This mutation results in an increase in phosphatase activity. Several lines were created and line 11 was used in subsequent experiments. Line 14 expresses the transgene at lower levels than line 11.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations