Version: 8.0.0
Date: Tue Jan 28 2025
Arg1tm1Pmu
MGI:3826847
Allele of Arg1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Arg1tm1Pmu

Species
Mus musculus
Symbol
Arg1tm1Pmu
Category
allele
Allele of gene
Arg1
Transgenic Constructs
None
Synonyms
  • Argfl
  • Arg1flox
Description
A loxP site was inserted upstream of exon 7 and a loxP-flanked neomycin selection cassette was inserted downstream of exon 8. Transient expression of cre recombinase removed the neomycin cassette, leaving exons 7 and 8 floxed. These exons encode in addition to the oligomerization domain, two highly conserved aspartic acid residues that are essential to the enzymatic activity of the gene product. Correct targeting was confirmed by genomic PCR.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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