Version: 8.0.0
Date: Tue Jan 28 2025
Runx2tm1Jals
MGI:3829607
Allele of Runx2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Runx2tm1Jals

Species
Mus musculus
Symbol
Runx2tm1Jals
Category
allele
Allele of gene
Runx2
Transgenic Constructs
None
Synonyms
  • Runx2neo7
Description
A floxed neo cassette was inserted into intron 7. The retention of the neo cassette results in a 55% to 70% decrease in relative full-length transcript expression in homozygotes and a 79% to 84% decrease in heterozygotes. Expression of a truncated transcript was observed, and reduced protein expression was confirmed by western blot analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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