Tlr6^m2Btlr

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Species

Mus musculus

Symbol

Tlr6^m2Btlr

Category

allele

Allele of gene

Tlr6

Transgenic Constructs

None

Synonyms

• m2sd1
• MALP-2 specific defect 1

Show All 3

Description

This mutation was discovered in a TLR Signaling Screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises an A to T transversion at nucleotide position 1501 of the gene (Genbank: NM_011604) that results in conversion of a triplet encoding arginine at amino acid position 457 to a termination codon (R457Ter), truncating the protein by 349 amino acids at its C terminus.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations