Version: 8.0.0
Date: Tue Jan 28 2025
Tlr6m2Btlr
MGI:3831304
Allele of Tlr6
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tlr6m2Btlr

Species
Mus musculus
Symbol
Tlr6m2Btlr
Category
allele
Allele of gene
Tlr6
Transgenic Constructs
None
Synonyms
  • m2sd1
  • MALP-2 specific defect 1
Description
This mutation was discovered in a TLR Signaling Screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises an A to T transversion at nucleotide position 1501 of the gene (Genbank: NM_011604) that results in conversion of a triplet encoding arginine at amino acid position 457 to a termination codon (R457Ter), truncating the protein by 349 amino acids at its C terminus.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations