Tlr6^m3Btlr

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Species

Mus musculus

Symbol

Tlr6^m3Btlr

Category

allele

Allele of gene

Tlr6

Transgenic Constructs

None

Synonyms

• m2sd2
• MALP-2 specific defect 2

Show All 3

Description

This mutation was discovered in a TLR Signaling Screen of G3 progeny of an ENU mutagenized male mouse. The mutation comprises a T to A transversion at nucleotide position 1301 of the gene (Genbank: NM_011604) that results in conversion of a triplet encoding leucine at amino acid position 190 to a termination codon (L190Ter), truncating the protein by 416 amino acids at its C terminus.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations