Allele/Variant

Sac3d1tm1Hnaka

Species
Mus musculus
Symbol
Sac3d1tm1Hnaka
Category
allele
Allele of gene
Sac3d1
Transgenic Constructs
None
Synonyms
  • SHD1-
Description
A SpeI-NotI fragment containing the proximal promoter and the upstream-portion of exon 1 was replaced with neomycin resistance gene. Correct targeting was confirmed by Southern blotting. Gene inactivation was confirmed by a failure to detect protein product in immunoblot analysis of thymocyte nuclear extracts collected from homozgytoes.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal B cell physiology
MGI
abnormal bone marrow cell morphology/developmentMGI
abnormal common myeloid progenitor cell morphologyMGI
abnormal mast cell physiologyMGI
increased erythroid progenitor cell numberMGI
increased T cell proliferation
MGI
spleen hyperplasia
MGI
thymus hyperplasia
MGI
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Disease Associations

No data available