Allele/Variant

Tg(Amhr2-Pik3ca*,-GFP)#Lzh

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

PIK3CA-Tg

Description

This transgene consists of the mouse Amhr2 promoter driving expression of a constitutively active form of mouse Pik3ca and, following an IRES, GFP. The constitutively active form of Pik3ca was created by the addition of the avian src myristoylation sequence (MGSSKSKPK) to the N terminus of Pik3ca. Twelve founders were generated. This record represents pooled data from multiple founder lines.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Pik3ca (Mmu)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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