Lipe^tm2Rze

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Species

Mus musculus

Symbol

Lipe^tm2Rze

Category

allele

Allele of gene

Lipe

Transgenic Constructs

None

Synonyms

None

Description

A floxed neomycin selection cassette was inserted in intron 1 and an additional loxP site was inserted 3' to exon 7. The resulting targeted ES cells were subjected to transient cre expression. The neomycin selection cassette was deleted leaving exons 2 through 7 flanked by loxP sites. In addition to this allele, transient expression provided recombinant ES cells in which exons 2-7 were also deleted. These cells were used to produce Lipe^tm1Rze.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations