Allele/Variant

Itga3tm1Hap

Species
Mus musculus
Symbol
Itga3tm1Hap
Category
allele
Allele of gene
Itga3
Transgenic Constructs
None
Synonyms
  • floxed alpha 3 intergrin
Description
LoxP sites were inserted around exon 3 and a FRT-flanked neomycin cassette was inserted downstream of exon 2. Founder mice were crossed with Flpe transgenic mice to remove the neomycin cassette. Gene expression in the absence of cre was unaffected as demonstrated by immunoblot analysis of homozygote kidney extracts. Cre-mediated removal of exon 3 will lead to an early termination codon in exon 4.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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