Allele/Variant

Tg(Thy1-MAPT*K369I)K3Gotz

Species
Mus musculus
Symbol
Tg(Thy1-MAPT*K369I)K3Gotz
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • K3
Description
The promoter was used to drive neuron-specific expression of a mutated human cDNA lacking exon 3, containing four microtubule binding domains, and nucleotide substitutions that result in an amino acid substitution of isoleucine for lysine at position 369 (K369). One line was created (K3).
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations