Dab1^tm5Cpr

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Species

Mus musculus

Symbol

Dab1^tm5Cpr

Category

allele

Allele of gene

Dab1

Transgenic Constructs

None

Synonyms

• Dab1^ab

Description

The exon encoding amino acids 23 through 69 was replaced with a construct containing a splice acceptor and a modified partial cDNA encoding the p80 splice form. The cDNA was modified to encode phenylalanines in place of two tyrosines residues (185, 198) that are phosphorylation sites. A floxed neomycin selection cassette was excised by transient cre expression.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations