Allele/Variant

Ext1tm1Vcs

Species
Mus musculus
Symbol
Ext1tm1Vcs
Category
allele
Allele of gene
Ext1
Transgenic Constructs
None
Synonyms
  • EXT1
  • Ext1e2neofl
Description
An inverted loxP site was introduced upstream to exon 2 in a genomic framgment containing the Ext1 gene. The fragment was then subcloned into a vector upstream of the forward-facing loxP-flanked neomycin resistance (Neo) cassette. The linearized targeti vector was electroporated into R1 ES cells. Cre-mediated recombination of this allele will result in inversion of exon2 of Ext1 and distruption of Ext1 function.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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