Allele/Variant

Tg(TcraTcrbAD10)1Hed

Species
Mus musculus
Symbol
Tg(TcraTcrbAD10)1Hed
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • AD10
Description
Productively rearranged Tcra and Tcrb genes were cloned from the murine T cell clone AD10 that is specific for pigeon cytochrome-c. In mice expressing I-Ek, or I-Eb, greater than 90% of thymocytes and T cells express the transgenic TCR. The alpha-chain of this transgenic TCR differs by one amino acid (a threonine instead of an alanine at position 99) to the alpha chain of the transgenic TCR expressed in Tg(TcrAND)53Hed transgenic mice.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

No data available

Disease Associations

No data available